A possible contribution of the locus coeruleus to arousal enhancement with mild exercise: evidence from pupillometry and neuromelanin imaging
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- Yudai Yamazaki
- Laboratory of Exercise Biochemistry and Neuroendocrinology , Faculty of Health and Sport Sciences, , 1-1-1 Tannoudai, Tsukuba, Ibaraki 305-8574 , Japan
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- Kazuya Suwabe
- Sport Neuroscience Division , Advanced Research Initiative for Human High Performance (ARIHHP), Faculty of Health and Sport Sciences, , 1-1-1 Tennoudai, Tsukuba, Ibaraki 305-8574 , Japan
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- Atsuko Nagano-Saito
- Laboratory of Exercise Biochemistry and Neuroendocrinology , Faculty of Health and Sport Sciences, , 1-1-1 Tannoudai, Tsukuba, Ibaraki 305-8574 , Japan
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- Kousaku Saotome
- Center for Cybernics Research, University of Tsukuba , 1-1-1 Tennoudai, Tsukuba, Ibaraki 305-8573 , Japan
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- Ryuta Kuwamizu
- Laboratory of Exercise Biochemistry and Neuroendocrinology , Faculty of Health and Sport Sciences, , 1-1-1 Tannoudai, Tsukuba, Ibaraki 305-8574 , Japan
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- Taichi Hiraga
- Laboratory of Exercise Biochemistry and Neuroendocrinology , Faculty of Health and Sport Sciences, , 1-1-1 Tannoudai, Tsukuba, Ibaraki 305-8574 , Japan
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- Ferenc Torma
- Laboratory of Exercise Biochemistry and Neuroendocrinology , Faculty of Health and Sport Sciences, , 1-1-1 Tannoudai, Tsukuba, Ibaraki 305-8574 , Japan
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- Kenji Suzuki
- Center for Cybernics Research, University of Tsukuba , 1-1-1 Tennoudai, Tsukuba, Ibaraki 305-8573 , Japan
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- Yoshiyuki Sankai
- Center for Cybernics Research, University of Tsukuba , 1-1-1 Tennoudai, Tsukuba, Ibaraki 305-8573 , Japan
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- Michael A Yassa
- Sport Neuroscience Division , Advanced Research Initiative for Human High Performance (ARIHHP), Faculty of Health and Sport Sciences, , 1-1-1 Tennoudai, Tsukuba, Ibaraki 305-8574 , Japan
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- Hideaki Soya
- Laboratory of Exercise Biochemistry and Neuroendocrinology , Faculty of Health and Sport Sciences, , 1-1-1 Tannoudai, Tsukuba, Ibaraki 305-8574 , Japan
書誌事項
- 公開日
- 2023
- 資源種別
- journal article
- 権利情報
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- https://creativecommons.org/licenses/by/4.0/
- DOI
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- 10.1093/texcom/tgad010
- 公開者
- Oxford University Press (OUP)
説明
<jats:title>Abstract</jats:title> <jats:p>Acute mild exercise has been observed to facilitate executive function and memory. A possible underlying mechanism of this is the upregulation of the ascending arousal system, including the catecholaminergic system originating from the locus coeruleus (LC). Prior work indicates that pupil diameter, as an indirect marker of the ascending arousal system, including the LC, increases even with very light-intensity exercise. However, it remains unclear whether the LC directly contributes to exercise-induced pupil-linked arousal. Here, we examined the involvement of the LC in the change in pupil dilation induced by very light-intensity exercise using pupillometry and neuromelanin imaging to assess the LC integrity. A sample of 21 young males performed 10 min of very light-intensity exercise, and we measured changes in the pupil diameters and psychological arousal levels induced by the exercise. Neuromelanin-weighted magnetic resonance imaging scans were also obtained. We observed that pupil diameter and psychological arousal levels increased during very light-intensity exercise, which is consistent with previous findings. Notably, the LC contrast, a marker of LC integrity, predicted the magnitude of pupil dilation and psychological arousal enhancement with exercise. These relationships suggest that the LC-catecholaminergic system is a potential a mechanism for pupil-linked arousal induced by very light-intensity exercise.</jats:p>
収録刊行物
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- Cerebral Cortex Communications
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Cerebral Cortex Communications 4 (2), tgad010-, 2023
Oxford University Press (OUP)
