<i>Arabidopsis</i> Type I Metacaspases Control Cell Death
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- Nuria S. Coll
- Department of Biology, 108 Coker Hall, University of North Carolina (UNC), CB 3280, Chapel Hill, NC 27599–3280, USA.
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- Dominique Vercammen
- VIB Department of Plant Systems Biology and Department of Plant Biotechnology and Genetics, Ghent University, 9052 Ghent, Belgium.
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- Andrea Smidler
- Department of Biology, 108 Coker Hall, University of North Carolina (UNC), CB 3280, Chapel Hill, NC 27599–3280, USA.
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- Charles Clover
- Department of Biology, 108 Coker Hall, University of North Carolina (UNC), CB 3280, Chapel Hill, NC 27599–3280, USA.
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- Frank Van Breusegem
- VIB Department of Plant Systems Biology and Department of Plant Biotechnology and Genetics, Ghent University, 9052 Ghent, Belgium.
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- Jeffery L. Dangl
- Department of Biology, 108 Coker Hall, University of North Carolina (UNC), CB 3280, Chapel Hill, NC 27599–3280, USA.
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- Petra Epple
- Department of Biology, 108 Coker Hall, University of North Carolina (UNC), CB 3280, Chapel Hill, NC 27599–3280, USA.
Description
<jats:title>The Yin and Yang of Plant Caspases</jats:title> <jats:p> The function of plant metacaspases, identified by limited sequence homology to the animal caspases that control cell death, has remained elusive. <jats:bold> Coll <jats:italic>et al.</jats:italic> </jats:bold> (p. <jats:related-article xmlns:xlink="http://www.w3.org/1999/xlink" ext-link-type="doi" page="1393" related-article-type="in-this-issue" vol="330" xlink:href="10.1126/science.1194980">1393</jats:related-article> ) have now elucidated the actions of two metacaspases in the small plant <jats:italic>Arabidopsis</jats:italic> . One metacaspase, AtMC1, promoted cell death, and the other, AtMC2, acted antagonistically to stall cell death. The results help to elucidate the mechanisms by which plants control cell survival during development and defend against pathogen attack. </jats:p>
Journal
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- Science
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Science 330 (6009), 1393-1397, 2010-12-03
American Association for the Advancement of Science (AAAS)
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Details 詳細情報について
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- CRID
- 1361137043828235904
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- ISSN
- 10959203
- 00368075
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- Data Source
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- Crossref