Rhodium(I)/Chiral Diene‐Catalyzed Enantioselective Addition of Boronic Acids to <i>N</i>‐Unsubstituted Isatin‐Derived Ketimines
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- Ryohei Yonesaki
- Graduate School of Pharmaceutical Sciences Kyushu University Maidashi 3-1-1 Higashi-ku Fukuoka 812-8582 Japan
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- Ibuki Kusagawa
- Graduate School of Pharmaceutical Sciences Kyushu University Maidashi 3-1-1 Higashi-ku Fukuoka 812-8582 Japan
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- Hiroyuki Morimoto
- Graduate School of Pharmaceutical Sciences Kyushu University Maidashi 3-1-1 Higashi-ku Fukuoka 812-8582 Japan
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- Tamio Hayashi
- Division of Chemistry and Biological Chemistry School of Physical and Mathematical Sciences Nanyang Technological University 21 Nanyang Link Singapore 637371 Singapore
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- Takashi Ohshima
- Graduate School of Pharmaceutical Sciences Kyushu University Maidashi 3-1-1 Higashi-ku Fukuoka 812-8582 Japan
書誌事項
- 公開日
- 2020-01-24
- 資源種別
- journal article
- 権利情報
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- http://onlinelibrary.wiley.com/termsAndConditions#vor
- DOI
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- 10.1002/asia.201901745
- 公開者
- Wiley
この論文をさがす
説明
<jats:title>Abstract</jats:title><jats:p>Enantioselective addition of boronic acids to <jats:italic>N</jats:italic>‐unsubstituted isatin‐derived ketimines was realized using rhodium(I)/chiral diene catalysts. The reactions can be performed in the presence of catalytic amounts of a base to give adducts in high yield with high enantioselectivity. Preliminary mechanistic information including a computational model to explain the observed enantioselectivity is also provided.</jats:p>
収録刊行物
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- Chemistry – An Asian Journal
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Chemistry – An Asian Journal 15 (4), 499-502, 2020-01-24
Wiley