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- Aleksandar Kibel
- Department for Heart and Vascular Diseases, Clinic of Internal Medicine, Osijek University Hospital, Osijek, Croatia
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- Kristina Selthofer-Relatic
- Department for Heart and Vascular Diseases, Clinic of Internal Medicine, Osijek University Hospital, Osijek, Croatia
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- Ines Drenjancevic
- Department of Physiology and Immunology, Faculty of Medicine, University of Osijek, Croatia
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- Tatjana Bacun
- Department of Internal Medicine, Faculty of Medicine, University of Osijek, Osijek, Croatia
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- Ivica Bosnjak
- Department for Heart and Vascular Diseases, Clinic of Internal Medicine, Osijek University Hospital, Osijek, Croatia
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- Dijana Kibel
- Department of Physiology and Immunology, Faculty of Medicine, University of Osijek, Croatia
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- Mario Gros
- Department of Physiology and Immunology, Faculty of Medicine, University of Osijek, Croatia
説明
<jats:p> The significance, mechanisms and consequences of coronary microvascular dysfunction associated with diabetes mellitus are topics into which we have insufficient insight at this time. It is widely recognized that endothelial dysfunction that is caused by diabetes in various vascular beds contributes to a wide range of complications and exerts unfavorable effects on microcirculatory regulation. The coronary microcirculation is precisely regulated through a number of interconnected physiological processes with the purpose of matching local blood flow to myocardial metabolic demands. Dysregulation of this network might contribute to varying degrees of pathological consequences. This review discusses the most important findings regarding coronary microvascular dysfunction in diabetes from pre-clinical and clinical perspectives. </jats:p>
収録刊行物
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- Journal of International Medical Research
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Journal of International Medical Research 45 (6), 1901-1929, 2017-01-12
SAGE Publications