Discovery of Novel Small-Molecule Inhibitors of BRD4 Using Structure-Based Virtual Screening
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- Lewis R. Vidler
- Division of Cancer Therapeutics, Cancer Research UK Cancer Therapeutics Unit, The Institute of Cancer Research, 15 Cotswold Road, Sutton, Surrey SM2 5NG, United Kingdom
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- Panagis Filippakopoulos
- Nuffield Department of Clinical Medicine, Structural Genomics Consortium, Oxford University, Old Road Campus Research Building, Headington, Oxford OX3 7DQ, United Kingdom
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- Oleg Fedorov
- Nuffield Department of Clinical Medicine, Structural Genomics Consortium, Oxford University, Old Road Campus Research Building, Headington, Oxford OX3 7DQ, United Kingdom
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- Sarah Picaud
- Nuffield Department of Clinical Medicine, Structural Genomics Consortium, Oxford University, Old Road Campus Research Building, Headington, Oxford OX3 7DQ, United Kingdom
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- Sarah Martin
- Nuffield Department of Clinical Medicine, Structural Genomics Consortium, Oxford University, Old Road Campus Research Building, Headington, Oxford OX3 7DQ, United Kingdom
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- Michael Tomsett
- Division of Cancer Therapeutics, Cancer Research UK Cancer Therapeutics Unit, The Institute of Cancer Research, 15 Cotswold Road, Sutton, Surrey SM2 5NG, United Kingdom
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- Hannah Woodward
- Division of Cancer Therapeutics, Cancer Research UK Cancer Therapeutics Unit, The Institute of Cancer Research, 15 Cotswold Road, Sutton, Surrey SM2 5NG, United Kingdom
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- Nathan Brown
- Division of Cancer Therapeutics, Cancer Research UK Cancer Therapeutics Unit, The Institute of Cancer Research, 15 Cotswold Road, Sutton, Surrey SM2 5NG, United Kingdom
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- Stefan Knapp
- Nuffield Department of Clinical Medicine, Structural Genomics Consortium, Oxford University, Old Road Campus Research Building, Headington, Oxford OX3 7DQ, United Kingdom
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- Swen Hoelder
- Division of Cancer Therapeutics, Cancer Research UK Cancer Therapeutics Unit, The Institute of Cancer Research, 15 Cotswold Road, Sutton, Surrey SM2 5NG, United Kingdom
収録刊行物
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- Journal of Medicinal Chemistry
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Journal of Medicinal Chemistry 56 (20), 8073-8088, 2013-10-03
American Chemical Society (ACS)
