Copper‐Catalyzed Cascade Cyclization for the Synthesis of Trifluoromethyl‐Substituted Spiro‐2<i>H</i>‐azirines from 1,6‐Enynes
書誌事項
- 公開日
- 2015-09-11
- 権利情報
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- http://onlinelibrary.wiley.com/termsAndConditions#vor
- DOI
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- 10.1002/adsc.201500510
- 公開者
- Wiley
この論文をさがす
説明
<jats:title>Abstract</jats:title><jats:p>A method for the synthesis of trifluoromethyl CF<jats:sub>3</jats:sub>‐substituted spirocyclic compounds containing with a unique quaternary carbon center from readily available starting materials has been developed. The reaction provides a facile access to 2<jats:italic>H</jats:italic>‐azirines <jats:italic>via</jats:italic> cascade cyclization. These compounds constitute a new class of functionalized synthetic intermediates, which can be used for the synthesis of various nitrogen‐containing heterocycles and biologically active CF<jats:sub>3</jats:sub>‐containing compounds.</jats:p><jats:p><jats:boxed-text content-type="graphic" position="anchor"><jats:graphic xmlns:xlink="http://www.w3.org/1999/xlink" mimetype="image/gif" position="anchor" specific-use="enlarged-web-image" xlink:href="graphic/mcontent.gif"><jats:alt-text>magnified image</jats:alt-text></jats:graphic></jats:boxed-text></jats:p>
収録刊行物
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- Advanced Synthesis & Catalysis
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Advanced Synthesis & Catalysis 357 (14-15), 3069-3075, 2015-09-11
Wiley