Metal‐Free Direct Aryltrifluoromethylation of Allylic Alcohols with Langlois’ Reagent through Concomitant 1,2‐Aryl Migration

  • Hong‐Li Huang
    State Key Lab of Urban Water Resource and Environment The Academy of Fundamental and Interdisciplinary Sciences Harbin Institute of Technology Harbin 150080 P. R. China
  • Hang Yan
    State Key Lab of Urban Water Resource and Environment The Academy of Fundamental and Interdisciplinary Sciences Harbin Institute of Technology Harbin 150080 P. R. China
  • Guo‐Lin Gao
    State Key Lab of Urban Water Resource and Environment The Academy of Fundamental and Interdisciplinary Sciences Harbin Institute of Technology Harbin 150080 P. R. China
  • Chao Yang
    State Key Lab of Urban Water Resource and Environment The Academy of Fundamental and Interdisciplinary Sciences Harbin Institute of Technology Harbin 150080 P. R. China
  • Wujiong Xia
    State Key Lab of Urban Water Resource and Environment The Academy of Fundamental and Interdisciplinary Sciences Harbin Institute of Technology Harbin 150080 P. R. China

書誌事項

公開日
2015-04-27
権利情報
  • http://onlinelibrary.wiley.com/termsAndConditions#vor
DOI
  • 10.1002/ajoc.201500096
公開者
Wiley

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説明

<jats:title>Abstract</jats:title><jats:p>A metal‐free and cost‐effective synthetic protocol for selective aryltrifluoromethylation of allylic alcohols with Langlois’ reagent (CF<jats:sub>3</jats:sub>SO<jats:sub>2</jats:sub>Na) through cascade trifluoromethyl radical addition/1,2‐aryl migration has been developed. The highlights of this procedure are operational simplicity, excellent functional group tolerance, and mild reaction conditions.</jats:p>

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