Synthesis of Oxindoles through Silver‐Catalyzed Trifluoromethylation–, Difluoromethylation– and Arylsulfonylation–Cyclization Reaction of <i>N</i>‐Arylacrylamides

書誌事項

公開日
2014-04-04
権利情報
  • http://onlinelibrary.wiley.com/termsAndConditions#vor
DOI
  • 10.1002/ejoc.201400087
公開者
Wiley

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説明

<jats:title>Abstract</jats:title><jats:p>Efficient synthesis of trifluoromethyl and difluoromethyl‐substituted oxindoles was achieved by reacting Langlois reagent or Baran reagent with <jats:italic>N</jats:italic>‐arylacrylamides. However, the reaction of aryl sulfinic acid sodium salts with <jats:italic>N</jats:italic>‐arylacrylamides did not give the desulfinative products, instead, aryl sulfonated products were produced.</jats:p>

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