A Versatile Toolkit to Produce Sensitive FRET Biosensors to Visualize Signaling in Time and Space
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- Rafael D. Fritz
- Institute of Biochemistry and Genetics, Department of Biomedicine, University of Basel, Mattenstrasse 28, 4058 Basel, Switzerland.
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- Michel Letzelter
- Institute of Biochemistry and Genetics, Department of Biomedicine, University of Basel, Mattenstrasse 28, 4058 Basel, Switzerland.
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- Andreas Reimann
- Institute of Biochemistry and Genetics, Department of Biomedicine, University of Basel, Mattenstrasse 28, 4058 Basel, Switzerland.
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- Katrin Martin
- Institute of Biochemistry and Genetics, Department of Biomedicine, University of Basel, Mattenstrasse 28, 4058 Basel, Switzerland.
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- Ludovico Fusco
- Institute of Biochemistry and Genetics, Department of Biomedicine, University of Basel, Mattenstrasse 28, 4058 Basel, Switzerland.
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- Laila Ritsma
- Hubrecht Institute–Royal Netherlands Academy of Arts and Sciences and University Medical Center Utrecht, Uppsalalaan 8, 3584 CT Utrecht, the Netherlands.
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- Bas Ponsioen
- Hubrecht Institute–Royal Netherlands Academy of Arts and Sciences and University Medical Center Utrecht, Uppsalalaan 8, 3584 CT Utrecht, the Netherlands.
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- Erika Fluri
- Institute of Biochemistry and Genetics, Department of Biomedicine, University of Basel, Mattenstrasse 28, 4058 Basel, Switzerland.
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- Stefan Schulte-Merker
- Hubrecht Institute–Royal Netherlands Academy of Arts and Sciences and University Medical Center Utrecht, Uppsalalaan 8, 3584 CT Utrecht, the Netherlands.
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- Jacco van Rheenen
- Hubrecht Institute–Royal Netherlands Academy of Arts and Sciences and University Medical Center Utrecht, Uppsalalaan 8, 3584 CT Utrecht, the Netherlands.
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- Olivier Pertz
- Institute of Biochemistry and Genetics, Department of Biomedicine, University of Basel, Mattenstrasse 28, 4058 Basel, Switzerland.
説明
<jats:p>Next-generation biosensors enable in vivo monitoring of ERK activity and detection of RhoA activity in small cellular extensions.</jats:p>
収録刊行物
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- Science Signaling
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Science Signaling 6 (285), rs12-, 2013-07-23
American Association for the Advancement of Science (AAAS)