CCND2 rearrangements are the most frequent genetic events in cyclin D1− mantle cell lymphoma
-
- Itziar Salaverria
- Department of Pathology, Hematopathology Unit, Hospital Clínic, Institut d'Investigacions Biomèdiques August Pi i Sunyer, University of Barcelona, Barcelona, Spain;
-
- Cristina Royo
- Department of Pathology, Hematopathology Unit, Hospital Clínic, Institut d'Investigacions Biomèdiques August Pi i Sunyer, University of Barcelona, Barcelona, Spain;
-
- Alejandra Carvajal-Cuenca
- Department of Pathology, Hematopathology Unit, Hospital Clínic, Institut d'Investigacions Biomèdiques August Pi i Sunyer, University of Barcelona, Barcelona, Spain;
-
- Guillem Clot
- Department of Pathology, Hematopathology Unit, Hospital Clínic, Institut d'Investigacions Biomèdiques August Pi i Sunyer, University of Barcelona, Barcelona, Spain;
-
- Alba Navarro
- Department of Pathology, Hematopathology Unit, Hospital Clínic, Institut d'Investigacions Biomèdiques August Pi i Sunyer, University of Barcelona, Barcelona, Spain;
-
- Alejandra Valera
- Department of Pathology, Hematopathology Unit, Hospital Clínic, Institut d'Investigacions Biomèdiques August Pi i Sunyer, University of Barcelona, Barcelona, Spain;
-
- Joo Y. Song
- Laboratory of Pathology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD;
-
- Renata Woroniecka
- Cytogenetic Laboratory, and
-
- Grzegorz Rymkiewicz
- Department of Pathology, The Maria Skłodowska-Curie Memorial Institute and Oncology Centre, Warsaw, Poland;
-
- Wolfram Klapper
- Department of Pathology, Hematopathology Section and Lymph Node Registry, Christian Albrechts University, Kiel, Germany;
-
- Elena M. Hartmann
- Institute of Pathology, University of Würzburg, Würzburg, Germany;
-
- Pierre Sujobert
- Henri Mondor Hospital, Creteil, France;
-
- Iwona Wlodarska
- Center for Human Genetics, KU Leuven, Leuven, Belgium;
-
- Judith A. Ferry
- Department of Pathology, Massachusetts General Hospital, Boston, MA;
-
- Philippe Gaulard
- Henri Mondor Hospital, Creteil, France;
-
- German Ott
- Department of Clinical Pathology, Robert-Bosch-Krankenhaus, and Dr Margarete Fischer-Bosch Institute of Clinical Pharmacology, Stuttgart, Germany;
-
- Andreas Rosenwald
- Institute of Pathology, University of Würzburg, Würzburg, Germany;
-
- Armando Lopez-Guillermo
- Department of Hematology, Hematopathology Unit, Hospital Clínic, Barcelona, Spain; and
-
- Leticia Quintanilla-Martinez
- Institute of Pathology, Eberhard-Karls-University of Tübingen, Tübingen, Germany
-
- Nancy L. Harris
- Department of Pathology, Massachusetts General Hospital, Boston, MA;
-
- Elaine S. Jaffe
- Laboratory of Pathology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD;
-
- Reiner Siebert
- Institute of Human Genetics, University Hospital Schleswig-Holstein Campus Kiel/Christian-Albrechts University, Kiel, Germany;
-
- Elias Campo
- Department of Pathology, Hematopathology Unit, Hospital Clínic, Institut d'Investigacions Biomèdiques August Pi i Sunyer, University of Barcelona, Barcelona, Spain;
-
- Sílvia Beà
- Department of Pathology, Hematopathology Unit, Hospital Clínic, Institut d'Investigacions Biomèdiques August Pi i Sunyer, University of Barcelona, Barcelona, Spain;
説明
<jats:title>Key Points</jats:title> <jats:p>This report describes a multidisciplinary study characterizing the largest series of cyclin D1− MCL patients. CCND2 translocations are the most frequent genetic event (55%) in cyclin D1− MCL.</jats:p>
収録刊行物
-
- Blood
-
Blood 121 (8), 1394-1402, 2013-02-21
American Society of Hematology