Asymmetric organocatalytic decarboxylative Mannich reaction using β-keto acids: A new protocol for the synthesis of chiral β-amino ketones
説明
<jats:p>The first decarboxylative Mannich reaction employing β-keto acids, catalyzed by cinchonine-derived bifunctional thiourea catalyst has been described. The desired β-amino ketones were obtained in excellent yields and with moderate to good enantioselectivities.</jats:p>
収録刊行物
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- Beilstein Journal of Organic Chemistry
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Beilstein Journal of Organic Chemistry 8 1279-1283, 2012-08-13
Beilstein Institut