Safety Assessment of Hydrolyzed Wheat Protein and Hydrolyzed Wheat Gluten as Used in Cosmetics
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- Christina Burnett
- Scientific Analyst/Writer, Cosmetic Ingredient Review, Cosmetic Ingredient Review, Washington, DC, USA
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- Wilma F. Bergfeld
- Expert Panel Member, Cosmetic Ingredient Review, Cosmetic Ingredient Review, Washington, DC, USA
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- Donald V. Belsito
- Expert Panel Member, Cosmetic Ingredient Review, Cosmetic Ingredient Review, Washington, DC, USA
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- Ronald A. Hill
- Expert Panel Member, Cosmetic Ingredient Review, Cosmetic Ingredient Review, Washington, DC, USA
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- Curtis D. Klaassen
- Expert Panel Member, Cosmetic Ingredient Review, Cosmetic Ingredient Review, Washington, DC, USA
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- Daniel C. Liebler
- Expert Panel Member, Cosmetic Ingredient Review, Cosmetic Ingredient Review, Washington, DC, USA
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- James G. Marks
- Expert Panel Member, Cosmetic Ingredient Review, Cosmetic Ingredient Review, Washington, DC, USA
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- Ronald C. Shank
- Expert Panel Member, Cosmetic Ingredient Review, Cosmetic Ingredient Review, Washington, DC, USA
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- Thomas J. Slaga
- Expert Panel Member, Cosmetic Ingredient Review, Cosmetic Ingredient Review, Washington, DC, USA
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- Paul W. Snyder
- Expert Panel Member, Cosmetic Ingredient Review, Cosmetic Ingredient Review, Washington, DC, USA
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- F. Alan Andersen
- Former Director, Cosmetic Ingredient Review, Cosmetic Ingredient Review, Washington, DC, USA
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- Bart Heldreth
- Executive Director, Cosmetic Ingredient Review, Washington, DC, USA
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説明
<jats:p> The Cosmetic Ingredient Review (CIR) Expert Panel (Panel) reviewed the product use, formulation, and safety data on hydrolyzed wheat protein and hydrolyzed wheat gluten, which function as skin- and hair-conditioning agents. The Panel determined that data from clinical and laboratory studies were sufficient to demonstrate that these ingredients will not elicit type 1 immediate hypersensitivity reactions in sensitized individuals and will not induce sensitization when the polypeptide lengths of the hydrolysates do not exceed 30 amino acids. The Panel concluded that hydrolyzed wheat gluten and hydrolyzed wheat protein are safe for use in cosmetics when formulated to restrict peptides to an average molecular weight of 3,500 Da or less. </jats:p>
収録刊行物
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- International Journal of Toxicology
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International Journal of Toxicology 37 (1_suppl), 55S-66S, 2018-05
SAGE Publications
