Nanosims Imaging: An Approach for Visualizing and Quantifying Lipids in Cells and Tissues
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- Cuiwen He
- Departments of Medicine, David Geffen School of Medicine, University of California, Los Angeles, California, USA
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- Loren G Fong
- Departments of Medicine, David Geffen School of Medicine, University of California, Los Angeles, California, USA
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- Stephen G Young
- Departments of Medicine, David Geffen School of Medicine, University of California, Los Angeles, California, USA
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- Haibo Jiang
- Centre for Microscopy, Characterisation, and Analysis, The University of Western Australia, Perth, Western Australia, Australia
説明
<jats:p> Over the past few decades, several approaches have been used to image lipids in cells and tissues, but most have limited spatial resolution and sensitivity. Here, we discuss a relatively new approach, nanoscale secondary ion mass spectrometry imaging, that makes it possible to visualize lipids in cells and tissues in a quantitative fashion and with high spatial resolution and high sensitivity. </jats:p>
収録刊行物
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- Journal of Investigative Medicine
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Journal of Investigative Medicine 65 (3), 669-672, 2017-03
SAGE Publications