Personalized Epigenomic Signatures That Are Stable Over Time and Covary with Body Mass Index
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- Andrew P. Feinberg
- Center for Epigenetics, Johns Hopkins School of Medicine, Baltimore, MD 21205, USA.
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- Rafael A. Irizarry
- Center for Epigenetics, Johns Hopkins School of Medicine, Baltimore, MD 21205, USA.
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- Delphine Fradin
- Center for Epigenetics, Johns Hopkins School of Medicine, Baltimore, MD 21205, USA.
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- Martin J. Aryee
- Center for Epigenetics, Johns Hopkins School of Medicine, Baltimore, MD 21205, USA.
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- Peter Murakami
- Center for Epigenetics, Johns Hopkins School of Medicine, Baltimore, MD 21205, USA.
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- Thor Aspelund
- Icelandic Heart Association, Kopavogur 201, Iceland.
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- Gudny Eiriksdottir
- Icelandic Heart Association, Kopavogur 201, Iceland.
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- Tamara B. Harris
- Intramural Research Program, National Institute of Aging, Bethesda, MD 21205, USA.
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- Lenore Launer
- Intramural Research Program, National Institute of Aging, Bethesda, MD 21205, USA.
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- Vilmundur Gudnason
- Icelandic Heart Association, Kopavogur 201, Iceland.
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- M. Daniele Fallin
- Center for Epigenetics, Johns Hopkins School of Medicine, Baltimore, MD 21205, USA.
説明
<jats:p>A genome-scale, gene-specific analysis of DNA methylation in the same individuals over a decade apart identifies a personalized epigenomic signature that may correlate with a common genetic trait.</jats:p>
収録刊行物
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- Science Translational Medicine
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Science Translational Medicine 2 (49), 49ra67-, 2010-09-15
American Association for the Advancement of Science (AAAS)
