Lead Optimization Studies on FimH Antagonists: Discovery of Potent and Orally Bioavailable Ortho-Substituted Biphenyl Mannosides
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- Zhenfu Han
- Department of Biochemistry and Molecular Biophysics, ‡Department of Molecular Microbiology, §Department of Pathology and Immunology, ∥Center for Women’s Infectious Disease Research, ⊥Department of Internal Medicine, and #Department of Anesthesiology, Washington University School of Medicine, 660 S. Euclid Avenue, Saint Louis, Missouri 63110, United States
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- Jerome S. Pinkner
- Department of Biochemistry and Molecular Biophysics, ‡Department of Molecular Microbiology, §Department of Pathology and Immunology, ∥Center for Women’s Infectious Disease Research, ⊥Department of Internal Medicine, and #Department of Anesthesiology, Washington University School of Medicine, 660 S. Euclid Avenue, Saint Louis, Missouri 63110, United States
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- Bradley Ford
- Department of Biochemistry and Molecular Biophysics, ‡Department of Molecular Microbiology, §Department of Pathology and Immunology, ∥Center for Women’s Infectious Disease Research, ⊥Department of Internal Medicine, and #Department of Anesthesiology, Washington University School of Medicine, 660 S. Euclid Avenue, Saint Louis, Missouri 63110, United States
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- Erik Chorell
- Department of Biochemistry and Molecular Biophysics, ‡Department of Molecular Microbiology, §Department of Pathology and Immunology, ∥Center for Women’s Infectious Disease Research, ⊥Department of Internal Medicine, and #Department of Anesthesiology, Washington University School of Medicine, 660 S. Euclid Avenue, Saint Louis, Missouri 63110, United States
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- Jan M. Crowley
- Department of Biochemistry and Molecular Biophysics, ‡Department of Molecular Microbiology, §Department of Pathology and Immunology, ∥Center for Women’s Infectious Disease Research, ⊥Department of Internal Medicine, and #Department of Anesthesiology, Washington University School of Medicine, 660 S. Euclid Avenue, Saint Louis, Missouri 63110, United States
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- Corinne K. Cusumano
- Department of Biochemistry and Molecular Biophysics, ‡Department of Molecular Microbiology, §Department of Pathology and Immunology, ∥Center for Women’s Infectious Disease Research, ⊥Department of Internal Medicine, and #Department of Anesthesiology, Washington University School of Medicine, 660 S. Euclid Avenue, Saint Louis, Missouri 63110, United States
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- Scott Campbell
- Department of Biochemistry and Molecular Biophysics, ‡Department of Molecular Microbiology, §Department of Pathology and Immunology, ∥Center for Women’s Infectious Disease Research, ⊥Department of Internal Medicine, and #Department of Anesthesiology, Washington University School of Medicine, 660 S. Euclid Avenue, Saint Louis, Missouri 63110, United States
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- Jeffrey P. Henderson
- Department of Biochemistry and Molecular Biophysics, ‡Department of Molecular Microbiology, §Department of Pathology and Immunology, ∥Center for Women’s Infectious Disease Research, ⊥Department of Internal Medicine, and #Department of Anesthesiology, Washington University School of Medicine, 660 S. Euclid Avenue, Saint Louis, Missouri 63110, United States
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- Scott J. Hultgren
- Department of Biochemistry and Molecular Biophysics, ‡Department of Molecular Microbiology, §Department of Pathology and Immunology, ∥Center for Women’s Infectious Disease Research, ⊥Department of Internal Medicine, and #Department of Anesthesiology, Washington University School of Medicine, 660 S. Euclid Avenue, Saint Louis, Missouri 63110, United States
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- James W. Janetka
- Department of Biochemistry and Molecular Biophysics, ‡Department of Molecular Microbiology, §Department of Pathology and Immunology, ∥Center for Women’s Infectious Disease Research, ⊥Department of Internal Medicine, and #Department of Anesthesiology, Washington University School of Medicine, 660 S. Euclid Avenue, Saint Louis, Missouri 63110, United States
収録刊行物
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- Journal of Medicinal Chemistry
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Journal of Medicinal Chemistry 55 (8), 3945-3959, 2012-04-13
American Chemical Society (ACS)