Effect of experimental diabetes on craniofacial growth in rats

書誌事項

公開日
2008-09
権利情報
  • https://www.elsevier.com/tdm/userlicense/1.0/
  • https://www.elsevier.com/legal/tdmrep-license
  • https://doi.org/10.15223/policy-017
  • https://doi.org/10.15223/policy-037
  • https://doi.org/10.15223/policy-012
  • https://doi.org/10.15223/policy-029
  • https://doi.org/10.15223/policy-004
DOI
  • 10.1016/j.archoralbio.2008.02.008
公開者
Elsevier BV

この論文をさがす

説明

The goal of this study was to assess the effect of type 1 diabetes mellitus (T1DM) on the craniofacial growth and skeletal maturation using the STZ-DM rat model.Experimental T1DM was induced in 3-week-old male Wistar rats by a single dose of 60 mg/kg body weight of streptozotocin (STZ). Lateral and dorsoventral X-rays of the head were taken at the age of 7 weeks. The X-rays were scanned, digitised and selected linear distances were measured and analysed statistically.In STZ-DM statistical analysis of results revealed a reduction in growth of most of the linear measurements in the neurocranium and mandible by X-ray analysis, and all measurements were significantly lower in viscerocranium.Uncontrolled T1DM reduces craniofacial growth, resulting in retardation of skeletal development.

収録刊行物

被引用文献 (9)*注記

もっと見る

問題の指摘

ページトップへ