The Inducible Costimulator (ICOS) Is Critical for the Development of Human T <sub>H</sub> 17 Cells
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- Chrystal M. Paulos
- Abramson Family Cancer Research Institute, Department of Pathology and Laboratory Medicine, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA.
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- Carmine Carpenito
- Abramson Family Cancer Research Institute, Department of Pathology and Laboratory Medicine, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA.
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- Gabriela Plesa
- Abramson Family Cancer Research Institute, Department of Pathology and Laboratory Medicine, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA.
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- Megan M. Suhoski
- Stanford University School of Medicine, Palo Alto, CA 94305–2296, USA.
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- Angel Varela-Rohena
- Abramson Family Cancer Research Institute, Department of Pathology and Laboratory Medicine, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA.
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- Tatiana N. Golovina
- Abramson Family Cancer Research Institute, Department of Pathology and Laboratory Medicine, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA.
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- Richard G. Carroll
- Abramson Family Cancer Research Institute, Department of Pathology and Laboratory Medicine, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA.
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- James L. Riley
- Abramson Family Cancer Research Institute, Department of Pathology and Laboratory Medicine, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA.
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- Carl H. June
- Abramson Family Cancer Research Institute, Department of Pathology and Laboratory Medicine, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA.
説明
<jats:p> The inducible costimulator ICOS is critical for the differentiation and expansion of human T <jats:sub>H</jats:sub> 17 cells and promotes the antitumor capacity of these cells. </jats:p>
収録刊行物
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- Science Translational Medicine
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Science Translational Medicine 2 (55), 55ra78-, 2010-10-27
American Association for the Advancement of Science (AAAS)
