Evaluation of Traditional Chinese Medicinal Plants for Anti-MRSA Activity with Reference to the Treatment Record of Infectious Diseases
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- Guo-Ying Zuo
- Research Center for Natural Medicines, Kunming General Hospital, PLA, Kunming 650032, China
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- Xin-Juan Zhang
- Research Center for Natural Medicines, Kunming General Hospital, PLA, Kunming 650032, China
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- Cui-Xian Yang
- Research Center for Natural Medicines, Kunming General Hospital, PLA, Kunming 650032, China
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- Jun Han
- Yunnan Traditional Chinese Medical College, Kunming 650500, China
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- Gen-Chun Wang
- Research Center for Natural Medicines, Kunming General Hospital, PLA, Kunming 650032, China
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- Zhong-Qi Bian
- Center for Infectious Diseases, Kunming General Hospital, PLA, Kunming 650032, China
説明
<jats:p>The in vitro antimicrobial activities of 30 Chinese medicinal plants were evaluated with reference to the treatment record of infectious diseases in the Traditional Chinese Medicine (TCM) literature. The plant materials were extracted with 80% ethanol and the extracts were primarily screened against conventional clinical pathogens like Staphylococcus aureus, Escherichia coli, Pseudomonas aeruginosa and Candida albicans by the agar diffusion method. Their inhibition zone diameters (IZDs, mm, 50 mg/mL) ranged from 2,048 by the standard broth microdilution method. The seven extracts from M. yunnanensis, S. sinensis, G. morella, E. daneillii, M. squamulata, S. arborescens and B. hancei were determined as the most active extracts, with MICs of 8–64 μg/mL. The results were in good agreement with their traditional applications in skin and other infections.</jats:p>
収録刊行物
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- Molecules
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Molecules 17 (3), 2955-2967, 2012-03-09
MDPI AG
