Interaction between α-linolenic acid-enriched oil and ACE inhibitor concerning the decrease in blood pressure in SHR
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- Matsuo Tatsuhiro
- Faculty of Agriculture, Kagawa University
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- Yagi Kanako
- Faculty of Agriculture, Kagawa University
書誌事項
- タイトル別名
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- Interaction between .ALPHA.-Linolenic Acid-Enriched Oil and ACE Inhibitor Concerning the Decrease in Blood Pressure in SHR
- Interaction between a linolenic acid enriched oil and ACE inhibitor concerning the decrease in blood pressure in SHR
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説明
α-Linolenic acid (ALA) has been reported to exhibit an antihypertensive effect. Angiotensin-converting enzyme inhibitor (ACEI) is also an antihypertensive agent. We evaluated the interaction between ALA-enriched oil (test oil) and ACEI concerning the decrease in blood pressure by administering test oil, ACEI, or test oil + ACEI to 7-week-old spontaneously hypertensive rats (SHR). After administration, the systolic pressure decreased significantly in all groups compared with the level before administration, but the diastolic pressure decreased significantly only in the test oil + ACEI group. No significant difference was noted in systolic or diastolic pressure among the 3 groups. These results suggest that the interaction between ALA-enriched oil and ACEI is limited. Our study suggested the safety of consuming foods containing a large amount of ALA in combination with hypotensive agents.<br>
収録刊行物
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- Journal of Oleo Science
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Journal of Oleo Science 57 (1), 11-14, 2008
公益社団法人 日本油化学会
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詳細情報 詳細情報について
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- CRID
- 1390001204093010560
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- NII論文ID
- 130000055443
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- NII書誌ID
- AA11503337
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- ISSN
- 13473352
- 13458957
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- NDL書誌ID
- 9304337
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- 本文言語コード
- en
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- データソース種別
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- JaLC
- NDL
- Crossref
- CiNii Articles
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- 抄録ライセンスフラグ
- 使用不可