Cytotoxic substances from two species of Japanese sea hares: chemistry and bioactivity
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- YAMADA Kiyoyuki
- Professor Emeritus, Nagoya University
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- OJIKA Makoto
- Graduate School of Bioagricultural Sciences, Nagoya University
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- KIGOSHI Hideo
- Graduated School of Pure and Applied Sciences, University of Tsukuba
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- SUENAGA Kiyotake
- Faculty of Science and Technology, Keio University
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抄録
From the sea hares belonging to two genera, Aplysia and Dolabella, a variety of new cytotoxic substances were isolated as minute constituents: their chemical structures were determined and their cytotoxicity was evaluated. Regarding the highly cytotoxic substances, further chemical and biological studies were performed that included their asymmetric chemical synthesis and elucidation of biological characteristics such as antitumor activity.<br><br>(Communicated by Satoshi OMURA, M.J.A.)
収録刊行物
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- Proceedings of the Japan Academy. Ser. B: Physical and Biological Sciences
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Proceedings of the Japan Academy. Ser. B: Physical and Biological Sciences 86 (3), 176-189, 2010
日本学士院
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詳細情報 詳細情報について
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- CRID
- 1390001204146704256
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- NII論文ID
- 130000264072
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- NII書誌ID
- AA00785485
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- ISSN
- 13492896
- 03862208
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- NDL書誌ID
- 10621854
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- 本文言語コード
- en
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- データソース種別
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- JaLC
- NDL
- Crossref
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- 抄録ライセンスフラグ
- 使用不可