β-lactamase and β-lactam antibiotics resistance in Acinetobacter antiratum(SYN.:A.calcoaceticus)
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- MOROHOSHI TOSHIRO
- Research Laboratories, Toyo Jozo Co., Ltd.
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- SAITO TETSU
- Research Laboratories, Toyo Jozo Co., Ltd.
書誌事項
- タイトル別名
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- .BETA.-Lactamase and .BETA.-lactam antibiotics resistance in Acinetobacter anitratum (syn.: A. Calcoaceticus).
- ベータ lactamase and ベータ lactam antibiotic
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抄録
The cephalosporin β-lactamase (cephalosporinase) produced by Acinetobacter was studied. The enzyme was partially purified by means of column chromatography and its properties were investigated. The enzyme was induced by benzylpenicillin, 6-aminopenicillanic acid and cephaloridine. Its molecular weight is 30, 000, its optimal temperature 40°C, and its optimal pH 7.25-7.50. Substrate specificity studies using various cephalosporins and penicillins, showed that the enzyme functioned as a cephalosporinase rather than penicillinase.
収録刊行物
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- The Journal of Antibiotics
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The Journal of Antibiotics 30 (11), 969-973, 1977
公益財団法人 日本感染症医薬品協会
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詳細情報 詳細情報について
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- CRID
- 1390001204155277824
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- NII論文ID
- 130003499307
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- NII書誌ID
- AA0069330X
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- COI
- 1:CAS:528:DyaE1cXjtlKnsA%3D%3D
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- ISSN
- 18811469
- 00218820
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- NDL書誌ID
- 1914729
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- PubMed
- 201599
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- 本文言語コード
- en
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- データソース種別
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- JaLC
- NDL
- Crossref
- PubMed
- CiNii Articles
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- 抄録ライセンスフラグ
- 使用不可