Interraction between Toxicant and Nutrition (II)

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  • 毒性物質と栄養との関係 (第2報)
  • ドクセイ ブッシツ ト エイヨウ ト ノ カンケイ 2 ノウヤク ノ セッシュリョウ ト セイタイナイ チクセキリョウ ト ノ カンケイ
  • Relationship between Concentrations of γ-BHC in Diet and Deposition of the Chemical in Animal Tissues
  • 農薬の摂取量と生体内蓄積量との関係

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Abstract

Rats were fed with a diet containing 0, 1, 10 and 100ppm of γ-BHC and sacrificed at regular intervals to determine resultant deposition of the chemical in their tissues.<BR>While the marked depression of growth was found by the administration of a diet containing 100ppm of the chemical to rats for 56 days, this phenomenon was not observed in the case of 1 and 10ppm.<BR>There were no correlations between the dietary levels of the chemical and the deposition in various tissues.<BR>The concentrations of the deposited chemical in various tissues were found to reach their equilibrium level after 3 to 7 days, administration in the case of 100ppm feeding. However, for 1 and 10ppm groups, the deposition was found to reach the highest level after 21 and 14 days' feeding, respectively, and to decrease slowly thereafter.

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