Improvement in Reliability of Probabilistic Test of Significant Differences in GeneChip Experiments
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- TODA Kyoko
- National Institute of Health Sciences
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- ISHIDA Seiichi
- National Institute of Health Sciences
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- NAKATA Kotoko
- National Institute of Health Sciences
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- MATSUDA Rieko
- National Institute of Health Sciences
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- SHIGEMOTO-MOGAMI Yukari
- National Institute of Health Sciences
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- OZAWA Shogo
- National Institute of Health Sciences
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- SAWADA Jun-ichi
- National Institute of Health Sciences
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- OHNO Yasuo
- National Institute of Health Sciences
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- INOUE Kazuhide
- National Institute of Health Sciences
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- SHUDO Koichi
- National Institute of Health Sciences
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- HAYASHI Yuzuru
- National Institute of Health Sciences
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A probabilistic test (FUMI theory) for GeneChip experiments has been proposed for selecting the genes which show significant differences in the gene expression levels between a single pair of treatment and control. This paper describes that the reliability of the judgment by the FUMI theory can be enhanced, when the selected genes are referred to biomolecular-functional networks of a commercial database. The genes judged as being differently expressed are grouped into a cluster in the biomolecular networks. It is also demonstrated that false positive genes have a trend in the networks to be isolated from each other, and also away from the clustered genes, since the false positive genes are randomly selected.
収録刊行物
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- Analytical Sciences
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Analytical Sciences 20 (4), 731-733, 2004
社団法人 日本分析化学会
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詳細情報 詳細情報について
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- CRID
- 1390001204257315968
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- NII論文ID
- 10012851136
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- NII書誌ID
- AA10500785
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- COI
- 1:CAS:528:DC%2BD2cXjsVGlurg%3D
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- ISSN
- 13482246
- 09106340
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- NDL書誌ID
- 6912306
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- PubMed
- 15116977
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- Web Site
- http://id.ndl.go.jp/bib/6912306
- https://ndlsearch.ndl.go.jp/books/R000000004-I6912306
- https://link.springer.com/content/pdf/10.2116/analsci.20.731.pdf
- https://link.springer.com/article/10.2116/analsci.20.731/fulltext.html
- http://www.jstage.jst.go.jp/article/analsci/20/4/20_4_731/_pdf
- https://search.jamas.or.jp/link/ui/2005259938
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- 本文言語コード
- en
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- データソース種別
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- JaLC
- NDL
- Crossref
- PubMed
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