書誌事項
- タイトル別名
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- Basal studies on the model of circular excisional wounds made on the dorsal skin of rats treated with hydrocortisone.
- Hydrocortisone フカ ラット ハイブ ヒフ エンケイ セツジョ
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説明
This study was performed to establish a circular excisional wound model treated with hydrocortisone (HC-P) and to estimate the following parameters in this model: wound area, hydroxyproline (Hyp) content, histological characteristics and microscopical measurements of histological sections. HC-P inhibited the reduction of wound area, the increase in Hyp content and proliferation of granulation tissue in a dose-dependent manner. The application of ZnO ointment significantly accelerated the reduction of wound area and the increased Hyp content in rats treated with HC-P. From these results, we concluded that this experimental model is useful for the objective evaluation of the efficacy of drugs that promote wound healing.
収録刊行物
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- 日本薬理学雑誌
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日本薬理学雑誌 98 (5), 369-377, 1991
公益社団法人 日本薬理学会
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詳細情報 詳細情報について
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- CRID
- 1390001204273565312
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- NII論文ID
- 130000758810
- 10005940968
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- NII書誌ID
- AN00198335
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- COI
- 1:CAS:528:DyaK38XksFyi
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- ISSN
- 13478397
- 00155691
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- NDL書誌ID
- 3750328
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- PubMed
- 1813368
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- 本文言語コード
- ja
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- データソース種別
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- JaLC
- NDL
- Crossref
- PubMed
- CiNii Articles
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- 抄録ライセンスフラグ
- 使用不可