Molecular Basis of Spatio-temporal Dynamics in Inositol 1,4,5-Trisphosphate-Mediated Ca〔2+〕Signalling
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- Iino Masamitsu
- Department of Pharmacology,Graduate School of Medicine,The University of Tokyo;and CREST,Japan Science and Technology Corporation,Tokyo 113-0033,Japan
書誌事項
- タイトル別名
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- Molecular Basis of Spatio-temporal Dynamics in Inositol 1,4,5-Trisphosphate-Mediated Ca2+ Signalling.
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抄録
Inositol 1, 4, 5−trisphosphate(IP3)−mediated Ca2+ signalling regulates many important cell functions, and the spatio−temporal dynamics of the Ca2+ signalling is a crucial factor for its versatility.The molecular mechanisms that control Ca2+ signalling are now being investigated, and I here describe the subtypes of IP3 receptors that have distinct functional properties and contribute to the diversity of Ca2+ signalling patterns.I also discuss the spatio−temporal dynamics of intracellular IP3 concentration, describing recent methodological advances in monitoring intracellular IP3 concentration.These findings highlight the potential importance of the spatio−temporal information of any signalling molecule.
収録刊行物
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- Jpn.J.Pharmacol.
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Jpn.J.Pharmacol. 82 (1), 15-20, 2000
公益社団法人 日本薬理学会
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詳細情報 詳細情報について
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- CRID
- 1390001204287286784
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- NII論文ID
- 10008182507
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- NII書誌ID
- AA00691188
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- COI
- 1:CAS:528:DC%2BD3cXotF2ksw%3D%3D
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- ISSN
- 13473506
- 00215198
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- NDL書誌ID
- 4966407
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- PubMed
- 10874583
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- Web Site
- http://id.ndl.go.jp/bib/4966407
- https://ndlsearch.ndl.go.jp/books/R000000004-I4966407
- https://api.elsevier.com/content/article/PII:S002151981930722X?httpAccept=text/xml
- https://api.elsevier.com/content/article/PII:S002151981930722X?httpAccept=text/plain
- https://www.jstage.jst.go.jp/article/jjp/82/1/82_1_15/_pdf
- https://search.jamas.or.jp/link/ui/2000141526
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- 本文言語コード
- en
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- データソース種別
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- JaLC
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