Inhibitory Effect of a Formulation Containing 0.5% Magnolignan (5,5'-dipropyl-biphenyl-2,2'-diol) on UV-induced Skin Pigmentation

DOI Web Site 2 Citations 8 References

Bibliographic Information

Other Title
  • マグノリグナン（５，５′‐ジプロピル‐ビフェニル‐２，２′‐ジオール）配合製剤の紫外線により生成される色素沈着に対する抑制効果
  • 治療 マグノリグナン(5,5'-ジプロピル-ビフェニル-2,2'-ジオール)配合製剤の紫外線により生成される色素沈着に対する抑制効果
  • チリョウ マグノリグナン 5 5 ジプロピル ビフェニル 2 2 ジオール ハイゴウ セイザイ ノ シガイセン ニ ヨリ セイセイ サレル シキソ チンチャク ニ タイスル ヨクセイ コウカ

Search this article

Description

A double-blind test was performed on human subjects to determine the efficacy of formulations containing 0.5% Magnolignan® (5,5'-dipropyl-biphenyl-2,2'-diol) for treatment of UV-induced pigmentation. Two adjacent test areas were selected on the inside of the upper arm of 43 subjects. A significant difference in the pigmentation score was observed after 3 weeks of application of a formulation containing 0.5% Magnolignan® in comparison with a placebo. Furthermore, the improvement in ΔL values were significantly different after 3 weeks compared with the placebo. No unfavorable skin reaction such as irritation, etc., was observed during the test period. In conclusion, the formulation containing 0.5% Magnolignan® was found to be safe and effective for topical application in treating UV-induced pigmentation. These data indicate that Magnolignan® is an effective whitening ingredient that can be used in cosmetics.

Journal

  • Nishi Nihon Hifuka

    Nishi Nihon Hifuka 68 (3), 288-292, 2006

    Western Division of Japanese Dermatological Association

Citations (2)*help

See more

References(8)*help

See more

Details 詳細情報について

Report a problem

Back to top