DRD4 VNTR polymorphism in Oceanic populations
-
- NAKA IZUMI
- Doctoral Program in Life System Medical Sciences, Graduate School of Comprehensive Human Sciences, University of Tsukuba, Tsukuba
-
- OHASHI JUN
- Doctoral Program in Life System Medical Sciences, Graduate School of Comprehensive Human Sciences, University of Tsukuba, Tsukuba
-
- KIMURA RYOSUKE
- Transdisciplinary Research Organization for Subtropical and Island Studies, University of the Ryukyus, Nakagami
-
- FURUSAWA TAKURO
- Graduate School of Asian and African Area Studies, Kyoto University, Kyoto
-
- YAMAUCHI TARO
- Graduate School of Health Sciences, Hokkaido University, Sapporo
-
- NAKAZAWA MINATO
- Department of Public Health, Graduate School of Medical Sciences, Gunma University, Maebashi
-
- NATSUHARA KAZUMI
- The Japanese Red Cross Akita College of Nursing, Akita
-
- ATAKA YUJI
- School of Policy Studies, Kwansei Gakuin University, Sanda
-
- NISHIDA NAO
- Department of Human Genetics, Graduate School of Medicine, The University of Tokyo, Tokyo Research Center for Hepatitis and Immunology, International Medical Center of Japan Konodai Hospital, Ichikawa
-
- ISHIDA TAKAFUMI
- Department of Biological Sciences, Graduate School of Science, The University of Tokyo, Tokyo
-
- INAOKA TSUKASA
- Department of Human Ecology, Faculty of Agriculture, Saga University, Saga
-
- MATSUMURA YASUHIRO
- Faculty of Health Care, Kiryu University, Midori
-
- OHTSUKA RYUTARO
- Japan Wildlife Research Center, Tokyo
書誌事項
- タイトル別名
-
- <i>DRD4</i> VNTR polymorphism in Oceanic populations
この論文をさがす
抄録
To study the origin of Polynesians and the gene flow from Polynesian ancestors to indigenous Melanesians, a 48-bp variable number of tandem repeats (VNTR) in exon 3 of the dopamine D4 receptor (DRD4) gene was investigated for six Austronesian (AN)-speaking populations—two in Tonga (Nuku’alofa and Ha’apai), three in Solomon Islands (Munda, Paradise, and Rawaki, of whom Rawaki was a Micronesian migrant group), and one in Papua New Guinea (Balopa), and one Non-Austronesian (NAN)-speaking population in Papua New Guinea (Gidra). In these Oceanic populations, six VNTR alleles with 2 (2R) to 11 (7R) repeats were observed. The most frequent DRD4 VNTR allele was the 4R allele, although the allele frequencies of 2R and 7R varied markedly among them, characterized by high frequencies of 7R and lack of 2R in NAN-speaking Melanesians (Gidra), and high frequencies of 2R and low or null frequencies of 7R in AN-speaking Polynesians (Nuku’alofa and Ha’apai) and Micronesians (Rawaki). The allele frequency distribution of DRD4 VNTR in Polynesians was similar to that in Aboriginal Taiwanese (Ami and Atayal), supporting the hypothesis that Polynesian ancestors were derived from Southeast Asians (probably Taiwanese). A principal component analysis for Southeast Asian and Oceanic populations based on the DRD4 VNTR allele frequencies revealed that AN-speaking Melanesian populations were genetically placed between two AN-speaking Polynesian and one NAN-speaking Melanesian populations. These results provide evidence of gene flow from Polynesian ancestors to indigenous Melanesians while Polynesian ancestors passed through Melanesia.
収録刊行物
-
- Anthropological Science
-
Anthropological Science 120 (2), 151-155, 2012
一班社団法人 日本人類学会
- Tweet
詳細情報 詳細情報について
-
- CRID
- 1390001204314071168
-
- NII論文ID
- 10031057349
-
- NII書誌ID
- AA11307827
-
- ISSN
- 13488570
- 09187960
-
- HANDLE
- 20.500.12000/46977
-
- NDL書誌ID
- 023894454
-
- 本文言語コード
- en
-
- データソース種別
-
- JaLC
- IRDB
- NDL
- Crossref
- CiNii Articles
- KAKEN
-
- 抄録ライセンスフラグ
- 使用不可