Diagnosis and Treatment of Actinic Keratosis

DOI 2 Citations 79 References
  • SAIDA Toshiaki
    <i>Professor Emeritus, Shinshu University School of Medicine</i>

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  • 日光角化症の診断と治療

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Description

Actinic keratosis (AK) is an early stage of squamous cell carcinoma (SCC) seen on the chronically sun-damaged skin of elderly persons. It is a common condition in Caucasians, and guidelines for the management have been published in Europe and the USA. In recent years, the number of AK patients has also been increasing in Japan due to the movement toward an aging society. Most AKs are harmless ; however, some of them progress to invasive SCC and induce problems in management, particularly in high-aged patients with various kinds of physical complications. Because we cannot identify which AK is high risk, appropriate treatment should be performed when we detect AK. In this article, the author first summarized the relevant data of recent basic research and the epidemiology of AK, and then described the clinical and histopathologic characteristics of AK in order to increase diagnostic accuracy. Thereafter the present status of treatment of AK was described in detail, which surely helps clinicians to manage AK adequately.[Skin Cancer (Japan) 2010 ; 25 : 214-231]

Journal

  • Skin Cancer

    Skin Cancer 25 (2), 214-231, 2010

    The Japanese Skin Cancer Society

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