A case of primary cutaneous marginal zone lymphoma
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- KAMIYA Hideki
- Division of Dermatology, Kizawa Memorial Hospital
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- KITAJIMA Yasuo
- Division of Dermatology, Kizawa Memorial Hospital
Bibliographic Information
- Other Title
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- Primary cutaneous marginal zone lymphomaと考えた1例
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Description
Herein, we report the case of a 66-year-old man with cutaneous B-cell pseudolymphoma. He had a history of an ill-defined red-brown plaque, which appeared on the right side of his chest seven years previously. The biopsy specimen revealed a dense, lymphocytic infiltrate admixed with eosinophils and focal reactive lymphoid follicles with cell atypia. Immunohistochemical findings showed that these cells were CD20+, CD79a+, bcl-2+, weakly bcl-6+, MUM-1-, Cyclin D-, CD10-, CD30-, and CD56-. Immunophenotypic studies did not show the presence of any phenotypic aberrance of the monotypic immunoglobulin (Ig) light chain. However, rearrangement of the DH7/JH gene was positive via polymerase chain reaction analysis. General examinations did not reveal any findings of malignant lymphoma. The plaques spontaneously regressed after a biopsy was performed. This case did not fulfill the criteria of cutaneous B-cell lymphoma, but the wide range of skin plaques should be considered worrisome for potential progression to true lymphoma, especially primary cutaneous marginal zone B lymphoma.[Skin Cancer (Japan) 2015 ; 30 : 163-167]
Journal
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- Skin Cancer
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Skin Cancer 30 (3), 163-167, 2015
The Japanese Skin Cancer Society
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Details 詳細情報について
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- CRID
- 1390001204336793984
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- NII Article ID
- 130005131673
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- ISSN
- 18843549
- 09153535
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- Text Lang
- ja
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- Data Source
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- JaLC
- Crossref
- CiNii Articles
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- Abstract License Flag
- Disallowed