ハムスターの体外培養卵巣におけるtranexamic acidの排卵抑制効果

DOI
  • 山海 直
    Department of Veterinary Physiology, College of Agriculture & Veterinary Medicine, Nihon University
  • 渡辺 靖浩
    Department of Veterinary Physiology, College of Agriculture & Veterinary Medicine, Nihon University
  • 金山 喜一
    Department of Veterinary Physiology, College of Agriculture & Veterinary Medicine, Nihon University
  • 遠藤 克
    Department of Veterinary Physiology, College of Agriculture & Veterinary Medicine, Nihon University
  • 佐久間 勇次
    Department of Veterinary Physiology, College of Agriculture & Veterinary Medicine, Nihon University

書誌事項

タイトル別名
  • An inhibitory effect of tranexamic acid on ovulation in hamster ovaries incubated in vitro

説明

It is reported as a hypothesis that, in the final stage of ovulation, theplasminogen activator acts on the follicular wall to rupture it up and thus toinduce ovulation. The authors applied the excited ovary to tranexamic acid, which is an anti-plasminogen activator, to examine if it would inhibitovulation. Ovaries were obtained from golden hamsters and incubated in vitro. Tranexamic acid was added to the medium at a concentration of 0.196. Inovaries excited at 21:00 and 23:00 of proestrus of the estrus cycle, ovulationrate was 25.096 and 91.696, and the average numburs of ova ovulated were0.25-0.12 and 1.58±0.26, respectively. The number of ova was significantlyfewer than the control.<BR>In this study, it was clear that tranexamic acid inhibited ovulation fromovaries in vitro. The present results indicated that ovulation in culturedovaries was inhibited by blooking plasminogen activator.

収録刊行物

詳細情報 詳細情報について

  • CRID
    1390001204339147008
  • NII論文ID
    130003839315
  • DOI
    10.14893/jmor1984.4.98
  • ISSN
    18846505
    02895439
  • データソース種別
    • JaLC
    • CiNii Articles
  • 抄録ライセンスフラグ
    使用不可

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