A Retrospective Study on Recurrent or New Intracranial Aneurysms after Neck Clipping

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  • 脳動脈瘤クリッピング術後の再発例・新生例の検討

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It has been recognized that surgically-treated, even successfully clipped, intracranial aneurysms may regrow in time. In this study, the authors have tried to determine how many surgically treated aneurysms are likely to recur. Between 1969 and 1992 they have clipped 417 saccular aneurysms in 359 patients. After excluding 26 patients who soon died postoperatively, of the remaining 333 patients, 257 patients (77%) were followed up and retrospec-tive review of these patients has revealed that 83 patients underwent IV-DSA to determine whether they had an aneurysmal recurrence. The follow-up period for those patients was 8.8±5.3 years (1〜25 years) . Five of these follow up patients (1.9%) were known to have experienced rebleeding, based on their medical records or from a telephone interview. In one of these five patients, an aneurysmal recurrence was confirmed by cerebral angiography. With regard to the ramaining 4 patients, cerebral angiography revealed 6 newly developed aneurysms. As a result of the postoperative IV-DSA study of 83 patients, 2 cases were diagnosed as having had an aneurysmal recurrence. An aneurysmal recurrence was seen proximal to the clip in one patient, and contralateral to the previous aneurysm in another patient. The reported incidence of an initial subarachnoid hemorrhage in the general population varies from 11 to 16/ 100,000 (population)/year. Based on our findings of a second subarachnoid hemorrhage in our surgically treated patients, we have roughly calculated the incidence of a recurrent subarachnoid hemorrhage to be about 221/ 100,000/year. Therefore, patients who have undergone aneurysmal surgery have a high risk of developing a new aneurysm and /or an aneurysmal recurrence. Considering the great length of time it takes for an aneurysm to recur, a long-term follow up of over ten years should be established. Further, IV-DSA evaluations have proven useful for evaluating an aneurysmal recurrence.

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