神経因性疼痛に対するカプサイシン軟膏の効果
書誌事項
- タイトル別名
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- Effect of Capsaicin Cream on Neuropathic Pain
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説明
Objective: The aim of this study was to evaluate whether 0.05% capsaicin cream could alleviate neuropathic pain that was unresponsive to conventional treatment. The changes of sleep, spirit, and activities of daily living, and side effects during capsaicin treatment were also studied.<br>Patients and methods: Capsaicin cream was applied to 12 patients: six with postherpetic neuralgia (PHN) and six with pain following nerve injury. The intensity of pain before, during, and after capsaicin treatment was measured by Visual Analogue Scale (VAS: 0=no pain, 100=severe pain).<br>Results: Median VAS scores before, during, and after treatment were 45, 10, and 10, respectively, for the PHN group, and 80, 40, and 50, respectively, for the nerve injury group. In both groups, median VAS scores were significantiy lower (p<0.05) during and after the treatment than those before treatment. Sleep, spirit, and activities of daily living were improved in 42%, 75%, and 58% of patients, respectively, during treatment. No severe side effects, except skin exfoliation in one patient, were observed. After capsaicin treatment, the pain recurred slowly but not significantly in the nerve injury group. No recurrence of pain was observed in the PHN group.<br>Conclusions: Our findings suggest that capsaicin cream is effective for treatment of neuropathic pain due to PHN and nerve injury.
収録刊行物
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- 日本ペインクリニック学会誌
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日本ペインクリニック学会誌 6 (1), 26-30, 1999
一般社団法人 日本ペインクリニック学会
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詳細情報 詳細情報について
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- CRID
- 1390001204458605824
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- NII論文ID
- 130004085924
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- ISSN
- 18841791
- 13404903
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- データソース種別
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- JaLC
- CiNii Articles
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- 抄録ライセンスフラグ
- 使用不可