書誌事項
- タイトル別名
-
- Accelerated blood clearance of PEGylated liposomes after repeated injection
- Accelerated blood clearance of PEGylated liposomes after repeated injection
- ポリエチレングリコール表面修飾リポソームの繰り返し投与時に発現するaccelerated blood clearance(ABC)現象
この論文をさがす
説明
We and a Dutch group have recently reported the accelerated blood clearance (ABC) phenomenon upon repeated injection of PEGylated liposomes, that is the enhanced accumulation of PEGylated liposomes in liver and consequently rapidly cleared the liposomes from blood circulation. The phenomenon is a general characteristic of liposomes and the induction of the phenomenon depends on the physicochemical property and dose of liposomes and animal species. In addition, our study indicated that the IgM secreted in response to first dose is involved in the occurrence of the phenomenon. In this article, our and a Dutch group's recent results related to the ABC phenomenon were described.
収録刊行物
-
- Drug Delivery System
-
Drug Delivery System 19 (6), 495-510, 2004
日本DDS学会
- Tweet
キーワード
詳細情報 詳細情報について
-
- CRID
- 1390001204640586880
-
- NII論文ID
- 10014117131
-
- NII書誌ID
- AN10084591
-
- ISSN
- 18812732
- 09135006
-
- 本文言語コード
- ja
-
- データソース種別
-
- JaLC
- Crossref
- CiNii Articles
-
- 抄録ライセンスフラグ
- 使用不可