A-2. 遺伝性球状赤血球症に関する研究

DOI

書誌事項

タイトル別名
  • Studies on Hereditary Spherocytosis
  • Effect of Chemical and Enzymic Modifiers on Passive Ion Permeability of Erythrocyte
  • Chemical及びEnzymic Modifierに対する赤血球のイオン受動透過性

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説明

Parachloromercuribenzenesulphonic acid (PCMBS), an agent which increases passive permeability of cations by reacting with sulfhydryl groups of the membrane, much less increases cation permeability in hereditary spherocytic (HS) red cells than normal red cells. Pronase which is thought to alterate the charged amino groups of the membrane, changes permeability of cations in the same degree with normal and HS red cells. Alteration of sulfhydryl groups of the membrane may be primarily involved in the changes of cation permeability in HS red cells.

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