Inactivation of Several Animal Viruses by Glutaraldehyde

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  • グルタールアルデヒドによる各種動物ウイルスの不活化
  • グルタールアルデヒド ニ ヨル カクシュ ドウブツ ウイルス ノ フカツカ

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The disinfecting activities of glutaraldehyde (GA) against several animal viruses were assessed by comparison with those of other disinfectants. The disinfecting activity of GA against rotavirus was analyzed at temperatures of 22 C and 37 C showing good results. At 4 C the disinfecting activity was poor. The presence of serum or tryptose phosphate broth as an organic substance in a viral suspension, had little affect on the virucidal activity of GA. GA efficiently inactivated rabies and parapox viruses and the capacity was comparable to that of sodium hypochlorite. In addition, it also had an inactivating capacity strongerthan that of sodium hypochlorite or iodophor against avian rotavirus and swine parvovirus, which were highly resistant to heat, various chemicals and pH. Moreover, its virucidal activity could persist for long periods of time even when diluted.

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