Relationship between Treatment and Prognosis of Canine Insulinoma: 22 Cases (1997-2006)

CHIJIWA Kohsaku, NISHIMURA Ryohei, MATSUKI Naoaki, SASAKI Nobuo

doi:10.2327/jvas.38.19

Bibliographic Information

Other Title

犬のインスリノーマ２２症例における治療法と予後の関連
イヌノインスリノーマ 22 ショウレイニオケルチリョウホウトヨゴノカンレン

Search this article

Description

Clinical features and relationship between treatment and prognosis were evaluated in 22 canine insulinomas. Nineteen dogs were middle or small-sized dogs weighing less than 20 kg, indicating a different tendency compared to several reports that large-breed dogs were commonly affected. Metastases were observed in 11 (69%) of 16 dogs surgically treated and the metastatic rate was higher than the past reports. One-year survival rate (56%) in dogs treated surgically was compatible with several reports and there is no difference of the survival interval compared to dogs treated medically alone. However, disease-free interval was significantly longer than that of dogs treated medically alone (P=0.0099). The clinical signs recurred within 3 months in 5 of 6 dogs treated medically alone. In addition, the result of the side effects by steroid and diazoxide may support a view that a medical treatment alone was not expected to a good quality of life. In conclusion, surgical treatment aimed at reducing tumor mass volume is useful for canine insulinoma unless there are diffuse metastases to the other organs. <br>

Journal

Japanese Journal of Veterinary Anesthesia & Surgery

Japanese Journal of Veterinary Anesthesia & Surgery 38 (2), 19-24, 2007

Japanese Society of Veterinary Anesthesia & Surgery

Keywords

Details 詳細情報について

Export