Factors Influencing Lower Extremity Muscle Strength in Interstitial Pneumonia Patients :

  • Takeichi Rie
    Department of Rehabilitation Medicine, St. marianna University School of Medicine Hospital
  • Yokoyama Hitoshi
    Department of Rehabilitation Medicine, St. marianna University School of Medicine Hospital
  • Yokoyama Yuri
    Department of Rehabilitation Medicine, St. marianna University School of Medicine Yokohama City Seibu Hospital
  • Kasahara Yusuke
    Department of Rehabilitation Medicine, St. marianna University School of Medicine Yokohama City Seibu Hospital
  • Omori Yoshitsugu
    Department of Rehabilitation Medicine, St. marianna University School of Medicine Yokohama City Seibu Hospital
  • Watanabe Yosuke
    Department of Rehabilitation Medicine, St. marianna University School of Medicine Hospital
  • Komase Yuko
    Department of Respiratory medicine, St. marianna University School of Medicine Yokohama City Seibu Hospital

Bibliographic Information

Other Title
  • 間質性肺炎患者の下肢筋力に影響を与える要因
  • -等尺性膝伸展筋力と呼吸機能,呼吸困難感,運動耐容能との関係-
  • The Association of Isometric Knee Extension Strength with Respiratory Function, Dyspnea and Exercise Capacity

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Purpose: The aim of this study was to clarify factors that can affect lower extremity muscle strength in stable interstitial pneumonia (IP). Methods: We examined the relationship between lower extremity muscle strength and respiratory function, dyspnea, and exercise tolerance in 107 patients with stable IP. Result: Isometric knee extension strength was associated with % DLco, the modified Medical Research Council (mMRC) dyspnea scale, and the 6-minute walk test. Moreover, logistic regression analysis to determine an dependent variable for whether a value of 0.50 kgf/kg of isometric knee extension strength caused movement impairment revealed the mMRC dyspnea scale grade as a factor that affected isometric knee extension strength (odds ratio 0.480, 95% CI 0.242-0.953). In addition, when the mMRC scale was Grade 1 or more, the results indicated that more than one half of the IP patients had a level of lower extremity muscle strength that fell below the level at which movement impairment begins. Conclusion: Lower limb muscle strength in IP patients was related to the level of respiratory failure, exercise tolerance, and dyspnea. Especially, it was revealed that when dyspnea is exacerbated in daily life, it can lead to a reduction in lower extremity muscle strength that may impair mobility.

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