書誌事項
- タイトル別名
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- Stability of Vitamin B1, and C in New Total Parenteral Nutrition Kit Products in Presence of Trace Elements
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説明
In many cases in the clinical setting,trace elements are mixed with TPN products.However,in such therapy the rapid oxidative decomposition of vitamin C is a problem.In view of this,we investigated the stability of vitamin C in a newly developed kit product for TPN (ELNEOPA No.1 and No.2 Injections) which contains trace elements in addition to glucose,electrolytes,amino acids,and vitamins.<br>We evaluated the stability of vitamin C after mixing all the ingredients of ELNEOPA in comparison with the control solution (admixture of commercial TPN solution containing vitamins and a trace element preparation).Though vitamin C rapidly decomposed in the control solution,it was stable in ELNEOPA,with not less than 90% of the labeled amount remaining 7 days after mixing.The container (plastic bag) of ELNEOPA is made from a high gas barrier film and we consider the stability of vitamin C in it to be due to the film preventing an increase in oxygen in the solution.Also,as at least 90% of the labeled amount of vitamin B1 was still present 7 days after mixing,ELNEOPA is considered to be a very useful preparation for TPN therapy,including that in the home.
収録刊行物
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- 医療薬学
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医療薬学 36 (1), 10-17, 2010
一般社団法人日本医療薬学会
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詳細情報 詳細情報について
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- CRID
- 1390001204777122816
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- NII論文ID
- 130004894738
- 80020745777
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- ISSN
- 18821499
- 1346342X
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- 本文言語コード
- ja
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- データソース種別
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- JaLC
- Crossref
- CiNii Articles
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- 抄録ライセンスフラグ
- 使用不可
