小柴胡湯を長期服用中，インターフェロンα・２ｂを併用投与後に間質性肺炎を呈したＣ型慢性肝炎の１例

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  • A case of chronic hepatitis C with interstitial pneumonitis after interferon .ALPHA.-2b administration during a long-term administration of sho-saiko-to.

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The patient was a 57-year-old male who had received syo-saiko-to due to liver dysfunction since 1983. He was diagnosed chronic hepatitis C in 1992 and administered interferon (IFN) α-2b 9MIU for 48 times. After the administration of IFN α-2b, the symptom of interstitial pneumonitis appeared. After the all medications were stopped, the symptoms and radiological findings were improved. The result of lymphocyte stimulation test was negative for IFN α-2b, but IFN-induced pneumonitis was strongly suspected from the clinical course. It should be noticed that IFN α-2b may induce interstitial pneumonitis, especially during the administration of sho-saiko-to like this case.

収録刊行物

  • 肝臓

    肝臓 35 (4), 302-308, 1994

    一般社団法人　日本肝臓学会

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