書誌事項
- タイトル別名
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- Clinical Relevance of Magnetic Resonance Imaging and Magnetic Resonance Spectroscopy for the Cirrhotic without Overt Hepatic Encephalopathy.
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説明
To clarify the changes of pallidal high intensity on T1-weighted magnetic resonance imaging (MRI) and brain metabolites on magnetic resonance spectroscopy (MRS) as related to the severity of hepatic functions, the concentrations of blood ammonia (B-NH3) and the levels of trace elements (Mn, Cu and Zn), 30 patients with liver cirrhosis without hepatic encephalopathy (HE) and 5 age-matched healthy control subjects underwent MRI and proton MRS. Pallidal high intensity (Pl index) and glutamine are higher in cirrhosis, and myo-inositol is lower than that of control statistically. In cirrhosis, there were statistically negative correlation between B-NH3 and myo-inositol and positive correlation between B-NH3 and glutamine. There was a statistically lower myo-inositol and higher Pl index, glutamine as the severity of hepatic functions increased. Furthermore there was a statistically positive correlation between Pl index and Mn. These data suggest that the changes of MRI and MRS findings already detected in cirrhosis without HE and these abnormalities may be reflect the B-NH3 and Mn metabolism and the severity of the hepatic functions.
収録刊行物
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- 肝臓
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肝臓 40 (4), 235-242, 1999
一般社団法人 日本肝臓学会
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キーワード
詳細情報 詳細情報について
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- CRID
- 1390001204791668864
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- NII論文ID
- 10005255596
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- NII書誌ID
- AN00047770
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- ISSN
- 18813593
- 04514203
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- 本文言語コード
- ja
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- データソース種別
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- JaLC
- Crossref
- CiNii Articles
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- 抄録ライセンスフラグ
- 使用不可
