経過中に著明なｌｏｗ　Ｔ３症候群を来した急性発症型自己免疫性肝炎の１例

DOI Web Site

書誌事項

タイトル別名
  • A case of acute onset autoimmune hepatitis complicated with low T3 syndrome.

この論文をさがす

説明

A 70-year-old woman was admitted to our hospital with general fatigue, anorexia and jaundice. Laboratory data on admission revealed acute hepatitis like abnormality such as GOT 1453IU/l, GPT 1031IU/l and total bilirubin 8.4mg/dl. There was no evidence of viral hepatitis type A, B or C. She was diagnosed as acute phase of autoimmune hepatitis because of increased serum IgG level (4246mg/dl), and positive serum anti-nuclelar-antibody. The liver biopsy specimen showed chronic active hepatitis.<BR>Since the serum level of free-T3 on admission was very low (1.36pg/dl) while those of free-T4 and TSH were normal, she was diagnosed to be complicated with low T3 syndrome. The oral administration of prednisolone started from 40mg/day improved her symptoms and abnormality of liver function tests. However, the serum F-T3 level was once decreased to undertactable level and then gradually increased with the tapering of prednisolone dosage.<BR>It is suggested that low T3 syndrome is associated with acute onset autoimmune hepatitis and it is accelerated by the corticosteroid hormone therapy.

収録刊行物

  • 肝臓

    肝臓 34 (2), 156-160, 1993

    一般社団法人　日本肝臓学会

キーワード

詳細情報 詳細情報について

問題の指摘

ページトップへ