健康食品「にんにく卵黄」によると思われる薬物性肝障害の1例

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  • A severe drug induced hepatitis caused by a dietary supplement "Nin-niku Ran-oh" made from garlic and egg yolk
  • ショウレイ ホウコク ケンコウ ショクヒン 「 ニンニクランオウ 」 ニ ヨル ト オモワレル ヤクブツセイ カン ショウガイ ノ 1レイ

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Dietary supplements are easily available and increasingly used, and adverse hepatic reactions have been reported following their intake.<br> A 60 years old woman who took some dietary supplements developed appetite loss, general fatigue, jaundice and subcutaneous hemorrhage together with a > 40-fold increase of transaminase levels and prothrombin time elongation. There were no evidence of viral hepatitis, autoimmune, metabolic or alcohol-related liver disorders. Drug-induced lymphocyte stimulation test was positive to the dietary supplement "Nin-niku Ran-oh", which is made from garlic and egg yolk. DDW-J 2004 drug-induced liver injury score was 10 and diagnosed as highly probable. Seven weeks after discontinuation of the supplements, the liver functions recovered to normal.<br>

収録刊行物

  • 肝臓

    肝臓 53 (11), 748-753, 2012

    一般社団法人　日本肝臓学会

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