TWO CASES OF GRANULOMATOUS MASTITIS

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  • 肉芽腫性乳腺炎の２例

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Case 1 : A 35-year-old woman presented with an 8×5cm mass in the lower inner quadrant of her left breast accompanied by skin redness and tenderness. Purulent nipple discharge, whose culture and cytology showed no microorganisms and no malignant cells, was also observed. Histological diagnosis of the induration was mastitis. As the induration and purulent discharge persisted despite 2 months of antibiotics and drainage therapy, the induration was extirpated. After that, the patient recovered. Case 2 : A 32-year-old woman presented with a 6×6cm mass and skin redness in the upper half of her left breast. A core needle biopsy specimen showed chronic inflammation without any malignant findings. Antibiotics and surgical drainage were performed, but those were not effective. As purulent discharge (no microorganisms) and the local tumor persisted, 3 months later the whole tumor was removed, and the patient recovered. Histologically widespread inflammation extended along the mammary ducts and multinucleated giant cells were seen in both cases. Histological diagnosis was granulomatous mastitis.<BR>There have been 42 Japanese cases of granulomatous mastitis including our two patients. Various effective treatments have been reported including steroids and Seton method, but there is no established treatment at present. So more research is needed regarding this disease.

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