放射線照射を併用しない術前化学療法（XELOX療法）で病理学的完全奏効が得られた局所進行直腸癌の1例

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  • A Case of Locally Advanced Rectal Cancer in which Pathological CR was Achieved after XELOX Neoadjuvant Chemotherapy

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A 34-year-old male was referred to us complaining of anal pain and bleeding. A detailed examination revealed a bulky tumor at the lower rectum with massive regional lymph node metastases. Two courses of XELOX therapy were administered as neoadjuvant chemotherapy. A subsequent examination revealed a significant decrease in size of the primary lesion and disappearance of swollen lymph nodes, and so we performed a laparoscopic super-low anterior resection of the rectum. The pathological examination revealed that there were no residual cancer cells, neither at the primary lesion nor the lymph nodes, and thus pathological CR was achieved. XELOX therapy was administered as adjuvant chemotherapy to the patient, who remains disease-free six months after the operation.

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