Clinical Evaluation of Idiopathic Interstitial Pneumonia and Interstitial Pneumonia Associated with Collagen Vascular Disease using Logistic Regression Analysis.

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  • ISHIOKA Shinichi
    the Second Department of Internal Medicine, Hiroshima University School of Medicine
  • NAKAMURA Kimihiko
    the Second Department of Internal Medicine, Hiroshima University School of Medicine
  • MAEDA Akihiro
    the Second Department of Internal Medicine, Hiroshima University School of Medicine
  • HIYAMA Keiko
    the Second Department of Internal Medicine, Hiroshima University School of Medicine
  • WATANABE Kenichiro
    the Second Department of Internal Medicine, Hiroshima University School of Medicine
  • MAEDA Hiroyuki
    the Second Department of Internal Medicine, Hiroshima University School of Medicine
  • HAYAKAWA Norihiko
    the Research Institute for Radiation Biology and Medicine, Hiroshima University
  • YAMAKIDO Michio
    the Second Department of Internal Medicine, Hiroshima University School of Medicine

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Objective To clarify the differences in the clinical features between idiopathic interstitial pneumonia (IIP) and interstitial pneumonia associated with collagen vascular diseases (CVD-IP).<br> Methods Symptoms, radiographic findings, pulmonary function, blood chemistry data including autoantibody, and bronchoalveolar lavage fluid (BALF) findings were compared using multiple logistic regression analysis.<br> Patients The subjects were 44 patients clinically diagnosed with IIP and 33 patients with CVD-IP.<br> Results The clinical features related to IIP were as follows: male sex, advanced age, past history of hypertension, presence of cough, exertional dyspnea, digital clubbing, an increased level of γ-globulin, decreased lung volume on chest X-ray, and typical type according to the criteria for IIP on chest X-ray. Increased levels of rheumatoid factor and total cell number in BALF were related to CVD-IP.<br> Conclusion These findings are considered to be useful to differentiate IIP and CVD-IP.<br>(Internal Medicine 39: 213-219, 2000)

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  • Internal Medicine

    Internal Medicine 39 (3), 213-219, 2000

    一般社団法人 日本内科学会

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