カプサイシンの抗酸化活性部位の特定に関する研究

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タイトル別名
  • Determination of Antioxidative Sites of Capsaicin
  • Two Different Approaches by Kinetics and Molecular Orbital Method
  • 速度論および分子軌道計算からのアプローチ

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抄録

We investigated the antioxidative sites of capsaicinhave the phenol moiety of CAP but has a acetamide (CAP) by discussing the structuring-activity of CAP and moiety, did not show the antioxidant activity. These using molecular orbital theory. First, the guaiacol results indicate that the phenolic hydrogen of CAP is the derivatives showed the effective antioxidant activity on site of antioxidant activity and its activity of CAP is the oxidation of cumene. Furthermore, CAP and these independent on the benzyl hydrogen and acetamide guaiacol derivatives have almost the same antioxidant moiety. In addition, these suggestions were confirmed activity in these experimental conditions. However, N -by calculating the electrostatic potential energy of CAP benzylacetamide, a related compound which does not using the molecular orbital energy method.

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