書誌事項
- タイトル別名
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- Effect of the Oral Administration of Vitamin B12 to Patients under Distal and Total Gastrectomy.
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Objectives: At high dosage, orally administered vitamin B12 is absorded by a gradient of concentration, not by an intrinsic factor. We studied the effect of oral administration of Mecobalamin (Methicobal) to patients undergoing distal and total gastrectomy. Methods: Eleven patients undergoing distal gastrectomy B-1 and 8 total gastrectomy R-Y were orally administered 1.5 mg/day of Mecobalamin, devided into 3 times/day, for 4 weeks. Blood levels of vitamin B12 were measured. Results: In distal gastrectomy, blood levels of vitamin B12, preceding and after 2 and 4 weeks administration of Mecobalamin, were 412+/-33, 581+/-62, and 701+/-94 pg/ml. In total gastrectomy, they were 312/-40, 440+/-34, and 469+/-30 pg/ml. Oral Mecobalamin administration increased vitamin B12 blood levels in patients undergoing both types of surgery. The correlation between the vitamin B12 blood levels before administration and increasing vitamin B12 after 4 weeks of administration was a significant positive correlation in distal gastrectomy but tended to be negative in total gastrectomy. Conclusion: Oral Mecobalamin administration at the usual dosage effectively provided patients undergoing distal and total gastrectomy with vitamin B12 and easily controlled at the clinic.
収録刊行物
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- 日本消化器外科学会雑誌
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日本消化器外科学会雑誌 34 (5), 439-444, 2001
一般社団法人 日本消化器外科学会
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詳細情報 詳細情報について
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- CRID
- 1390001204915926272
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- NII論文ID
- 130004343563
- 110001341044
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- NII書誌ID
- AN00192066
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- ISSN
- 13489372
- 03869768
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- 本文言語コード
- ja
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- データソース種別
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- JaLC
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- 使用不可