A Liver Metastasis 18 Years after Resection for Gastrointestinal Stromal Tumor of the Small Intestine

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  • 術後18年で肝再発を来した小腸gastrointestinal stromal tumorの1例

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<p>An 84-year-old woman was referred to our hospital for further examination and treatment of a liver mass, which was detected incidentally by abdominal US in June, 2016. In 1998, she underwent partial resection of the small intestine with a 12-cm mass, which was found to arise from the wall of the small intestine and the pathology was consistent with gastrointestinal stromal tumor (GIST). A CT scan showed a 98×80-mm mass in the right lobe of the liver. A core needle biopsy could not determine the existence of the characteristic spindle cells of GIST, however, her surgical history and the CT scan suggested liver metastasis from the GIST of the small intestine. We performed right hepatectomy, and immunohistochemical staining on histopathological examination revealed positive staining with c-kit, confirming a diagnosis of metastatic GIST. This case was a liver metastasis after a disease-free interval of 18 years. Long term follow-up, therefore, seems to be necessary for patients with a history of GIST tumor resection.</p>

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