進行性骨化性筋炎の1例
書誌事項
- タイトル別名
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- Myositis ossificans progressiva, a case report and clinical observation of diphosphonate therapy.
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Myositis ossificans progressive is a rare children's desease, characterized by slowly progressive and multiple ectopic ossification of connective tissues. The cause is unknown and there is no recognized treatment.<br>Recently we have treated a case of myositis ossificans progressiva. A 33-year-old male visited our hospital complaining of difficulty in walking and right side coxalgia. Ectopic ossifications developed from the age of about 14 years, and restriction of motion of spine and joints progressed year by year.<br>There were malformations of great toes which had been noted at birth. The spine was ankylosing and ROM of joints of extremities was severely restricted. Plasma alkaline phosphatase was higher, but plasma calcium and phosphorus were normal. X-rays and bone scintigrams showed multiple ectopic ossifications.<br>We treated this case by 20mg/kg/day of etidronate disodium (ethane-1-hydroxy-1. 1-diphosphonate, “EHDP”) for 3 months along with physical therapy. These treatments gave him a remission of right side coxalgia and widened the range of motion in some joints.<br>We concluded that diphosphonate therapy was effective to some extent in this case.
収録刊行物
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- 整形外科と災害外科
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整形外科と災害外科 35 (2), 678-683, 1986
西日本整形・災害外科学会
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詳細情報 詳細情報について
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- CRID
- 1390001204937005568
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- NII論文ID
- 130001635095
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- ISSN
- 13494333
- 00371033
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- 本文言語コード
- ja
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- データソース種別
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- JaLC
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- 抄録ライセンスフラグ
- 使用不可