急性末梢神経障害に対して用いたソル・メドロールによる紅斑型薬疹の3例について

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  • Three cases of drug-induced eruption due to Solu-Medrol.

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説明

We report 3 cases of extremely rare, delayed, drug-induced eruption caused by Solu-Medrol ® (methylprednisolone sodium succinate) to treat acute peripheral neuropathy. One developed into extremely serious erythroderma requiring systemic management. We studied other corticosteroid preparations possibly causing allergic reactions and considered antigenicity based on chemical structure. We assumed the first case was one in which the prednisolone skeleton acted as an antigen regardless of the methyl and succinate groups.

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